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谭碧娥

时间: 2019/12/02   作者:   点击:

个人简介:

谭碧娥,教授。主要从事猪肠道发育和营养调控。先后主持国家自然科学基金青年、面上项目、国家科技支撑计划专题、973项目子课题、国家重点研发计划子课题等多项。近年来以第一/通讯作者发表SCI收录论文50多篇, SCI论文合计引用1000多次,单篇最高被引200多次;参编著作4部,申请发明专利4项,获国家自然科学奖二等奖(排名第2)、中华农业科技奖一等奖(排名第5)、湖南省自然科学一等奖(排名第2)和二等奖(排名第3)以及中科院青年创新促进会优秀会员、中科院广州分院优秀青年科学家奖、中国科学院院长优秀奖。现为美国动物科学学会会员、中国畜牧兽医学会动物营养学分会理事、动物营养生理与代谢过程湖南省重点实验室学术委员会委员、宁乡市生物制造产业专家指导委员会委员。入选教育部长江学者奖励计划青年学者、国家万人计划科技创新领军人才、科技部创新人才推进计划、湖南省科技创新领军人才等。

 

教育及科研经历:

2001.07                        动物医学学      农学学士    湖南农业大学

2010.07                      动物生态营养    理学博士    中国科学院亚热带农业生态所

 

研究经历:

200802-200901        访问学者              美国德州农工大学

201612-201712        访问学者              美国加州大学戴维斯分校

 

主要研究方向:

1. 肠道发育和更新的信号传导途径

2. 肠道营养感应利用及生理免疫

3. 肠道菌群与宿主互作调控猪重要性状形成机制

 

联系方式:

Emailbietan@@hunau.edu.cnbietan0412@hotmail.com

地址:湖南农业大学第二教学楼502

 

代表性论文(近3年):

1.       Wang X, Tan B*, Liao P, Cui Z, Zhang S, Li X, Yin Y, Xiao D*. Functional bioactive substance improves the growth performance, antioxidant capacity and immune function of growth retardation pigs. Food and Agricultural Immunology, 2020, 31(1):329-340.

2.       Hussain T, Yuan D*, Tan B*, Murtaza G, Rahu N, Kalhoro MS, Kalhoro D, Yin Y. Eucommia ulmoides flavones (EUF) abrogated enterocyte damage induced by LPS involved in NF-κB signaling pathway. Toxicology In-vitro, 2020, 62:104674.

3.       Hussain T, Tan B*, Murtaza G, Liu G, Rahu N, Kalhoro MS, Kalhoro DH, Adebowale TO, Mazhar MU, Rehman Z, Martínez Y, Khan SA, Yin Y. Flavonoids and Type 2 Diabetes: Evidence of efficacy in clinical and animal studies and delivery strategies to enhance their therapeutic efficacy. Pharmacological Research, 2020,152: 10462.

4.       谭碧娥,伍树松,贺建华,印遇龙. 地方猪耐粗饲料和肉质性状形成的微生物代谢机制. 动物营养学报,202032(7) doi:10.3969/j.issn.1006-267x.2020.07.000.

5.       罗振福, 贺建华, 谭碧娥*. 甜菜粕的资源化利用及其在猪营养中的应用. 家畜生态学报, 2020, 41(1):81-85.

6.       Qi M, Tan B*, Wang J, Liao S, Li J, Liu Y, Yin Y. Post-natal growth retardation associated with impaired gut hormone profiles, immune and antioxidant function in pigs. Frontiers in Endocrinology, 2019, 10:660.

7.       Xiao DF, Yuan DX, Tan BH, Wang J, Liu YH, Tan BE*. The role of Nrf2 signaling pathway in Eucommia ulmoides flavones regulating oxidative stress in the intestine of piglets. Oxidative Medicine and Cellular Longevity, 2019, 2019:Article ID 9719618

8.       Qi M, Tan B*, Wang J, Li J, Liao S, Yan J, Liu Y, Yin Y. Small intestinal transcriptome analysis revealed changes of genes involved in nutrition metabolism and immune responses in growth retardation piglets. Journal of Animal Science, 2019, 97:3795-3808.

9.       Ren W, Xia Y, Chen S, Wu G, Bazer FW, Zhou B, Tan B*, Zhu G, Deng J, Yin Y*. Glutamine metabolism in macrophages: a novel target for obesity/type 2 diabetes. Advances in Nutrition, 2019, 10:321-330.

10.   Ren W, Liao Y, Ding X, Jiang Y, Yan J, Xia Y, Tan B*, Lin Z, Duan J, Jia X, Yang G, Deng J, Zhu C, Hardwidge PR, Li J, Zhu G*, Yin Y*. Slc6a13 deficiency promotes Th17 responses during intestinal bacterial infection. Mucosal Immunology, 2019, 12:531-544.

11.   Chen S, Tan B*, Xia Y, Liao S, Wang M, Yin J, Wang J, Xiao H, Qi M, Bin P, Liu G, Ren W*, Yin Y. Effects of dietary gamma-aminobutyric acid supplementation on the intestinal functions in weaning piglets. Food & Function, 2019, 10:366-378.

12.   肖昊,吴苗苗,王丽,谭碧娥*. 哺乳动物雷帕霉素靶蛋白信号通路影响精氨酸调控猪肠上皮细胞能量代谢的机制. 动物营养学报,2019, 31(3): 1266-1277. 

13.   Liu H, Tan B*, Huang B, Li J, Wang J, Liao P, Guan G, Ji P, Yin Y*. Involvement of CaSR activation in the alleviation of intestinal inflammation in piglets model by dietary aromatic amino acid supplementation. British Journal of Nutrition, 2018, 120(12):1321-1331.

14.   Li J, Tan B*, Tang Y, Liao P, Yao K, Ji P, Yin Y*. Extraction and identification of the chyme proteins in the digestive tract of growing pigs. Science China Life Sciences, 2018, 61(11): 1396-1406.

15.   Duan Y, Tan B*, Li J, Liao P, Huang B, Li F, Xiao H, Liu Y, Yin Y. Optimal branched-chain amino acid ratio improve cell proliferation and protein metabolism of porcine enterocytesin vivo and in vitro. Nutrition, 2018, 54:173-181.

16.   Tang Y, Tan B*, Li G, Li J, Ji P, Yin Y*. The regulatory role of MeAIB in protein metabolism and the mTOR signaling pathway in porcine enterocytes. International Journal of Molecular Sciences. 2018, 19, 714.

17.   Ren WK, Wang P, Yan JM, Liu G, Zeng BH, Hussain T, Peng C, Yin J, Li TJ, Wei H, Zhu GQ, Reiter RJ, Tan BE*, Yin YL*. Melatonin alleviates weanling stress in mice: Involvement of intestinal microbiota. Journal of Pineal Research, 2018, 64(2):e12448.

18.   谭碧娥,任文凯,印遇龙*. 胃肠道褪黑素分泌及其生理功能. 动物营养学报,2018, 30(4): 1207-1216.

19.   谭碧娥, 王婧, 印遇龙*. 仔猪肠道发育和氨基酸营养调控机制. 农业现代化研究, 2018, 39(6): 970-976.

20.   Tan BE, Liu HL, He GZ, Xiao H, Xiao DF, Liu YH, Wu JP, Fang J*, Yin YL*. Alanyl-glutamine but not glycyl-glutamine improves the proliferation of enterocytes as glutamine substitution in vitro. Amino Acids, 2017, 49(12):2023-2031.

21.   Yuan DX, Hussain T, Tan B*, Liu YH, Ji P, Yin YL. The evaluation of antioxidant and anti-inflammatory effects of Eucommia Ulmoides flavones using diquat-challenged piglets model. Oxidative Medicine and Cellular Longevity, 2017, 2017:Article ID 8140962.

22.   Hussain T, Tan B*, Yin YL*, Liu G, Murtaza G, Rahu N, Saleem M. Modulatory mechanism of polyphenols and Nrf2 signaling pathway in LPS challenged pregnancy disorders. Oxidative Medicine and Cellular Longevity, 2017, 2017:Article ID 8254289.

23.   Hussain T, Tan B*, Ren W, Rahu N, Dad R, Kalhoro DH, Yin YL*. Polyamines: therapeutic perspectives in oxidative stress and inflammatory diseases. Amino Acids, 2017, 49(9): 1457-1468.

24.   Ren W, Liu G, Chen S, Yin J, Wang J, Tan BE*, Wu G, Bazer FW, Peng Y, Li T, Reiter RJ*, Yin Y*. Melatonin signaling in T cells: Functions and applications. Journal of Pineal Research, 2017,62(3):e12394.

25.   Tan BE, Yin YL. Environmental sustainability analysis and nutritional strategies of animal production in China. Annual Review of Animal Biosciences, 2017, 5:171-184.

26.   Ren W, Yin J, Xiao H, Chen S, Liu G, Tan B*, Li N, Peng Y, Li T*, Zeng B, Li W, Wei H, Yin Z, Wu G, Hardwidge P, Yin Y*. Intestinal microbiota derived-GABA mediates interleukin-17 expression during enterotoxigenic Escherichia coli (ETEC) infection. Frontiers in Immunology, 2017, 7:685.

27.   Ren WK. Liu G, Yin J, Tan BE*, Wu GY, Bazer FW, Peng Y, Yin YL*. Amino-acid transporters in T-cell activation and differentiation. Cell Death & Disease, 2017, 8, e2655.

28.   Hussain T, Tan BE*, Ren WK, Rahu N, Kalhoro DH, Yin YL. Exploring polyamines: Functions in embryo/fetal development. Animal Nutrition, 2017, 3:7-10.

 

荣誉奖励:

12018年,壳寡(聚)糖对动物营养生理的调控作用及机理研究,湖南省自然科学二等奖,排名第3

22016年,猪日粮功能性氨基酸代谢与生理功能调控机制研究,国家自然科学奖二等奖(排名第22016-Z-105-2-03-R02

32014-2015 年,猪氨基酸营养功能的研究与技术集成推广,中华农业科技奖一等奖,排名第5

42013年,猪氨基酸营养功能的基础研究,湖南省自然科学一等奖,排名第2

52015年,长沙市自然科学优秀学术成果一等奖

62009年,中国科学院院长优秀奖

72017年,中科院广州分院优秀青年科学家奖

 

在研项目:

2019.12-2024.12   湖南农业大学人才引进科研启动费,500万元

2019.1-2021.12      湖南省重点研发计划项目现代农业实用技术和产品走出去” ”2018WK2070),80万元

2018.1-2020.12      国家万人计划科技创新领军人才,80万元

2017.1-2020.12 国家重点研发计划子课题有益菌代谢产物对仔猪肠道发育及功能的调控2017YFD0500503),30.2万元

2017.1-2020.12             国家自然科学基金面上项目“AMPKmTORC1介导氨基酸调控仔猪小肠黏膜能量利用与损伤修复31672433),76.8万元

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